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When you lose weight through any method, a portion of that weight comes from lean tissue (muscle and bone) rather than fat alone

Energy Levels and Fatigue A common side effect of GLP-1 medications is fatigue, often caused by the significant reduction in calories

doi: 10.1111/j.1748-1716.2010.02150.x

In subjects with higher body fat percentages, longer needles (1.52) may be necessary to ensure intramuscular delivery rather than inadvertent subcutaneous injection